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加齢歯科学分野

分野の紹介

外来診療や在宅訪問診療など、多職種連携を伴う様々な保健・医療の実践を通じ、高齢者を対象とする歯科口腔保健・医療のあり方、超高齢社会における歯科口腔保健・医療を通じた多様な社会貢献のあり方を模索しています。歯科口腔保健と健康・QoLの関連を解明する疫学研究、高齢者の口腔機能の維持向上の改善口腔機能の測定・解析・評価の実用的価値を高める研究にも力を注いでいます。

   ▲ 残存歯数と歯周病重篤度の海馬萎縮速度への影響

教員構成

主な研究テーマ

  • 歯科口腔保健と健康・QoLの関連や因果関係に関する研究
  • 多様なモダリティを応用した口腔機能の測定・解析・評価法の開発研究
  • 多職種連携に基づく高齢者歯科医療の供給体制に関する研究
  • 口腔機能評価に基づく適切な食品テクスチャー選択に関する研究

最近の業績

(2024)

  1. Fukuyama Y, Komiyama T, Ohi T, Hattori Y. Association between oral health and nutritional status among older patients receiving home-visit dental care who require long-term care. J Oral Sci, 2024; 66(2): 130-133.
  2. Komiyama T, Gallagher JE, Hattori Y. Relationship between tooth loss and progression of frailty: Findings from the English longitudinal study of aging, Archs Gerontol Geriatr, 2024; 127: 105572. 10.1016/j.archger.2024.105572.

(2023)

  1. Yamaguchi S, Murakami T, Satoh M, Komiyama T, Ohi T, Miyoshi Y, Endo K, Hiratsuka T, Hara A, Tatsumi Y, Totsune T, Asayama K, Kikuya M, Nomura K, Hozawa A, Metoki H, Imai Y, Watanabe M, Ohkubo T, Hattori Y. Associations of Dental Health with the progression of hippocampal atrophy in community-dwelling individuals: The Ohasama Study. Neurol. 2023 Sep 5;101(10):e1056-e1068. 10.1212/WNL.0000000000207579.

(2022)

  1. Ohi T, Murakami T, Komiyama T, Miyoshi Y, Endo K, Hiratsuka T, Satoh M, Asayama K, Inoue R, Kikuya M, Metoki H, Hozawa A, Imai Y, Watanabe M, Ohkubo M, Hattori Y. Oral health-related quality of life is associated with the prevalence and development of depressive symptoms independent of dentition status and dental visits in older Japanese individuals: The Ohasama Study. Gerodontol, 2022 Jun; 39(2): 204-212. 10.1111/ger.12557.
  2. Komiyama T, Ohi T, Ito W, Miyoshi Y, Hiratsuka T, Matsuyama S, Tsuji I, Watanabe M, Hattori Y. Relationship between maximum occlusal force and gastrointestinal cancer in community-dwelling older Japanese adults. Sci Rep, 2022 Jan 10;　12(1):　440. doi: 10.1038/s41598-021-04158-y.
  3. Park JW, Hamoda MM, Almeida FR, Wang Z, Wensley D, Alalola B, Alsaloum M, Tanaka Y, Huynh NT, Conklin AI. Socioeconomic inequalities in pediatric obstructive sleep apnea. J Clin Sleep Med, 2022; 18(2): 637–645.
  4. Yamada S, Komiyama T, Ohi T, Murakami T, Miyoshi Y, Endo K, Hiratsuka T, Hara A, Satoh M, Tatsumi Y, Inoue R, Asayama K, Kikuya M, Hozawa A, Metoki H, Imai Y, Ohkubo T, Hattori Y. Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study. J Periodontal Res. 2022 Jun;57(3):615-622. 10.1111/jre.12990. Epub 2022 Apr 6.

(2021)

  1. Yamaguchi S, Horigome Y, Endo K, Komagata M, Komai S, Komaki K, Miyata H, Sugano K, Ito S, Itabashi S, Sato H, Okahashi M, Kishi S, Abe R, Hattori Y. Caregiver-reported dementia as a predictor of oral health among patients receiving home-visit dental treatment: A retrospective cohort study. Clin Exp Dent Res, 2021;7:49–55. 10.1002/cre2.333.
  2. Tanji F, Komiyama T, Ohi T, Hattori Y, Watanabe M, Lu Y, Tsuji I. The association between number of remaining teeth and maintenance of successful aging in Japanese older people: a 9-year longitudinal study. Tohoku J Exp Med, 2020; 252(3): 245-252. 10.1620/tjem.252.245
  3. Ito Y, Hong G, Tsuboi A, Kawai Y, Kondo H, Nomura T, Kimoto S, Gunji A, Suzuki A, Ohwada G, Minakuchi S, Sato Y, Suzuki T, Kimoto K, Hoshi N, Saita M, Yoneyama Y, Sato Y, Morokuma M, Okazaki J, Maeda T, Nakai K, Ichikawa T, Nagao K, Fujimoto K, Murata H, Kurogi T, Takase K, Nishimura M, Nishi Y, Murakami M, Hosoi T, Hamada T. Multivariate analysis reveals oral health-related quality of life of complete denture wearers with denture adhesives: a multicenter randomized controlled trial. J Prosthod Res, 2021;65(3):353-359. 10.2186/jpr.JPR_D_20_00132.
  4. Ito W, Komiyama T, Ohi T, Hiratsuka T, Sone T, Tsuji I, Watanabe M, Hattori Y.　Relationship between oral health and fractures in community-dwelling older Japanese adults. J Am Med Dir Assoc, 2021 Feb 13;S1525-8610(21)00108-0. 10.1016/j.jamda.2021.01.058.
  5. Nakamura M, Aoyama N, Yamaguchi S, Sasano Y. Expression of tartrate-resistant acid phosphatase and cathepsin K during osteoclast differentiation in developing mouse mandibles. Biomed Res, 2021 Feb 10; 42(1): 13-21.
  6. Yamaguchi S, Watanabe M, Hattori Y. Statistical parametric mapping of three-dimensional local activity distribution of skeletal muscle using magnetic resonance imaging (MRI). Sci Rep 2021 Feb 26; 11(1): 4808.
  7.  

(2020)

  1. Takamasa Komiyama, Takashi Ohi, Yoshitada Miyoshi, Yasutake Tomata, Shu Zhang, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Verification of the criteria for reduced occlusal force to diagnose oral hypofunction in older Japanese people: A prospective cohort study on incident functional disability. J Oral Rehabil, 2020; 47: 989- 997. 10.1111/joor.13021.
  2. Takamasa Komiyama, Takashi Ohi, Takako Hiratsuka, Yoshitada Miyoshi, Yasutake Tomata, Shu Zhang, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Cognitive impairment and depressive symptoms lead to biases in self-evaluated masticatory performance among community-dwelling older Japanese adults: the Tsurugaya Project. J Dent, 2020; 99: 103403. 10.1016/j.jdent.2020.103403.
  3. Tanaka Y, Almeida FR. What can a dentist and dental sleep apnea researcher do under COVID-19 lockdown? J Clin Sleep Med, 2020; 16(9): 1641-1643. 10.5664/jcsm.8604.

(2019年)

  1. Takamasa Komiyama, Takashi Ohi, Yasutake Tomata, Fumiya Tanji, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Dental status is associated with incident functional disability in community-dwelling older Japanese: a prospective cohort study using propensity score matching. Journal of Epidemiology, 2019 Jan 25.
  2. Nao Furukawa, Yoshihiko Ito, Yasue Tanaka*, Wakana Ito, Yoshinori Hattori. Preliminary exploration for evaluating acuity of oral texture perception. Journal of Texture Studies, 2019 Mar 13; 1-7.
  3. Gaku Ohwada, Shunsuke Minakuchi, Yusuke Sato, Hisatomo Kondo, Taro Nomura, Akito Tsuboi, Guang Hong, Yoshihiko Itoh, Yasuhiko Kawai, Suguru Kimoto, Atsuko Gunji, Asako Suzuki, Tetsuya Suzuki, Katsuhiko Kimoto, Noriyuki Hoshi, Makiko Saita, Yoshikazu Yoneyama, Yohei Sato, Masakazu Morokuma, Joji Okazaki, Takeshi Maeda, Kenichiro Nakai, Tetsuo Ichikawa, Kan Nagao, Keiko Fujimoto, Hiroshi Murata, Tadafumi Kurogi, Kazuhiro Yoshida, Masahiro Nishimura, Yasuhiro Nishi, Mamoru Murakami, Toshio Hosoi, Taizo Hamada. Subjective evaluation of denture adhesives: A multicenter randomized controlled trial. JDR Clinical & Translational Research, 2019 Apr 11:2380084419837607. doi: 10.1177/2380084419837607.
  4. Takashi Ohi, Takamasa Komiyama, Yoshitada Miyoshi, Takahisa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. The association between bilateral maximum occlusal force and all-cause mortality among community-dwelling older adults: The Tsurugaya project. Journal of Prosthodontic Research, 10.1016/j.jpor.2019.08.005.
  5. Takako Hiratsuka, Takamasa Komiyama*, Takashi Ohi, Fumiya Tanji, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Contribution of systemic inflammation and nutritional status to the relationship between tooth loss and mortality in a community-dwelling older Japanese population: a mediation analysis of data from the Tsurugaya Project. Clinical Oral Investigations, 10.1007/s00784-019-03072-y. Accepted 30 August 2019, First Online 04 September 2019
  6. Yasuhiro Nishi, Taro Nomura, Mamoru Murakami, Yasuhiko Kawai, Masahiro Nishimura, Hisatomo Kondo, Yoshihiko Ito, Akito Tsuboi, Guang Hong, Suguru Kimoto, Atsuko Gunji, Asako Suzuki, Gaku Ohwada, Shunsuke Minakuchi, Yusuke Sato, Tetsuya Suzuki, Katsuhiko Kimoto, Noriyuki Hoshi, Makiko Saita, Yoshikazu Yoneyama, Yohei Sato, Masakazu Morokuma, Joji Okazaki, Takeshi Maeda, Kenichiro Nakai, Tetsuo Ichikawa, Kan Nagao, Keiko Fujimoto, Hiroshi Murata, Tadafumi Kurogi, Kazuhiro Yoshida, Toshio Hosoi, Taizo Hamada. Effect of denture adhesives on oral moisture: A multicenter randomized controlled trial. Journal of Prosthodontis Research 2019 Sep 6. pii: S1883-1958(19)30311-1. 10.1016/j.jpor.2019.08.004.
  7. Tsuyoshi Fujii, Satoshi Yamaguchi*, Yul-wan Sung, Makoto Watanabe, Yoshinori Hattori. Correlation between changes in the transverse relaxation time and electromyographic measurements of the superficial masseter and temporal muscles. Magnetic Resonance in Medical Sciences, Article ID: tn.2019-0035, 10.2463/mrms.tn.2019-0035.
  8. 伊藤佳彦, 古川奈緒, 伊藤和佳奈, 田中恭恵*, 服部佳功. とろみ調整食品の添加が口腔のざらつき感覚に及ぼす影響. 日本全身咬合学会雑誌 2019; 25(2): 44―48.

(2018年)

  1. Satoshi Yamaguchi, Chika Okada, Yoshihiko Watanabe, Makoto Watanabe, Yoshinori Hattori. Analysis of masticatory muscle coordination during unilateral single-tooth clenching using muscle functional magnetic resonance imaging. Journal of Oral Rehabilitation, 2018 Jan; 45(1): 9―16.
  2. Feng Luo, Guang Hong, Hiroyuki Matsui, Kosei Endo, Qianbing Wan, Keiichi Sasaki. Initial osteoblast adhesion and subsequent differentiation on zirconia surfaces are regulated by integrins and heparin-sensitive molecule. Int J Nanomedicine, 2018 Nov 19; 13: 7657-7667.
  3. Takashi Ohi, Takamasa Komiyama, Yoshitada Miyoshi, Takahasa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Maximum Occlusal Force and Incident Functional Disability in Older Adults: The Tsurugaya Project. JDR Clinical & Translational Research, 2018 Apr; 3(2): 195―202.
  4. Shigeto Koyama, Takeshi Fuji, Takashi Ohi, Kenji Kadowaki, Nobuhiro Yoda, Keiichi Sasaki. Practice-Based Longitudinal Study of Multifactorial Risk Assessment for Periodontal Condition and Survival of Remaining Teeth in Patients with Removable Partial Dentures. International Journal of Prosthodontics, 2018 September/October; 31(5): 502-8.
  5. Sho Saito, Takashi Ohi, Takahisa Murakami, Takamasa Komiyama, Yoshitada Miyoshi, Kosei Endo, Michihiro Satoh, Kei Asayama, Ryusuke Inoue, Masahiro Kikuya, Hirohito Metoki, Yutaka Imai, Takayoshi Ohkubo, Yoshinori Hattori. Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the Ohasama study. BMC Oral Health, 2018 Aug 20; 18(1): 142.
  6. Takamasa Komiyama, Takashi Ohi, Yoshitada Miyoshi, Takahisa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Relationship between status of dentition and incident functional disability in an elderly Japanese population: prospective cohort study of the Tsurugaya Project. Journal of Prosthodontic Research, 2018 Oct; 62(4): 443―448.

(2017年)

  1. J Liu, G Hong, YH Wu, Kosei Endo, JM Han, H Kumamoto, T Wada, H Kato, P Gao, Keiichi Sasaki. A novel method of surface modification by electrochemical deoxidation: Effect on surface characteristics and initial bioactivity of zirconia. J Biomed Mater Res B Appl Biomater. 2017 Nov; 105(8): 2641―2652.
  2. 伊藤佳彦, 遠藤耕生, 田中恭恵, 山口哲史, 服部佳功. 舌―硬口蓋間のテクスチャー感覚と舌乳頭の形態的特徴との関係: 予備的研究. 日本顎口腔機能学会雑誌 2017; 23(2): １―11.
  3. 猪狩洋平, 服部佳功. 加齢に伴う最大咬合力の変化: メタ解析による検討. 東北大学歯学雑誌 2017; 34(2)/35(1): 10―14.
  4. 田中恭恵, 古川奈緒, 服部佳功. 嚥下障害者用増粘剤（とろみ調整食品）が咀嚼能率に及ぼす影響 ～ピーナッツ咀嚼における検討～. 東北大学歯学雑誌 2017; 34(2)/35(1): 15―19.
  5. 山口哲史, 岡田知佳, 渡部芳彦, 渡辺誠, 服部佳功. mfMRIによる咀嚼筋局所活動分布における多様性の可視化と共通傾向の解析. 東北大学歯学雑誌 2017; 34(2)/35(1): 20―26.

(2016年)

  1. Chika Okada, Satoshi Yamaguchi, Yoshihiko Watanabe, Makoto Watanabe, Yoshinori Hattori. Evaluation of masticatory activity during unilateral single tooth clenching using muscle functional magnetic resonance imaging. Journal of Oral Rehabilitation, 2016 Aug; 43(8): 583―590.
  2. Minoru Takahashi, Satoshi Yamaguchi, Tsuyoshi Fujii, Makoto Watanabe, Yoshinori Hattori. Contribution of each masticatory muscle to the bite force determined by magnetic resonance imaging using a novel metal-free bite force gauge and an index of total muscle activity. Journal of Magnetic Resonance Imaging, 2016 Oct; 44(4): 804―813.
  3. Takamasa Komiyama, Takashi Ohi, Yoshitada Miyoshi, Takahisa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Association between tooth loss, receipt of dental care, and functional disability in an elderly Japanese population: The Tsurugaya Project. Journal of the American Geriatrics Society, 2016 Dec; 64(12): 2495-2502.
  4. 服部佳功, 枝広あや子, 渡邊裕, 平野浩彦, 古屋純一, 中島純子, 田村文誉, 北川昇, 堀一浩, 原哲也, 吉川峰加, 西恭宏, 永尾寛, 市川哲雄, 櫻井薫（一般社団法人日本老年歯科医学会ガイドライン委員会）. 認知症患者の歯科治療に対する疑問と問題点: Clinical Question調査から. 老年歯科医学 2016; 31(1): 3―8.

分野問い合わせ

E-mail：yoshinori.hattori.b4＊tohoku.ac.jp（＊を＠に変えてください。）
TEL：022-717-8396
FAX：022-717-8396

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