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加齢歯科学分野

分野の紹介

邦人寿命の著しい延伸とは対蹠的に高齢者の口腔環境改善は遅々として進まず、たとえば開始から20年以上を経た8020運動は目標達成の見通しすら立たない。歯の喪失の主因をなす齲蝕と歯周病はいずれも感染症であり、口腔衛生を主軸に据えた歯科口腔保健の推進は合理的だが、その効果が十分ではない現況に鑑みれば、別途の方策の必要は明らかであろう。

当分野は、口腔保健と全身保健の関連を大規模縦断疫学研究によって追及する一方、口腔機能の維持回復を高齢者歯科口腔保健の重要な方策と位置づけ、実効性ある介入手段の提案に向けた研究を進めている。

今後の歯科保健医療において、医療・介護・福祉ほか多様な専門職種との緊密な連携が一層求められることは疑われない。臨床においては、病院内外での診療の実践を通じて、その具体的で実現可能なあり方を模索している。

教員構成

主な研究テーマ

  • 大規模コホート研究に基づく歯科口腔保健と全身保健との関連および因果関係の解析
  • 多様なモダリティを応用した口腔機能の新規評価方法の開発
  • 口腔機能特性とその加齢変化に関する研究
  • 高齢者における歯科診療の適応とその評価方法･基準の策定に向けた検討
  • 多職種連携に基づく高齢者歯科医療の供給体制に関する検討

最近の業績

(2020年)

  1. Takamasa Komiyama, Takashi Ohi, Yoshitada Miyoshi, Yasutake Tomata, Shu Zhang, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Verification of the criteria for reduced occlusal force to diagnose oral hypofunction in older Japanese people: A prospective cohort study on incident functional disability. Journal of Oral Rehabilitation, 2020 May 19. doi: 10.1111/joor.13021.
  2. Takamasa Komiyama, Takashi Ohi, Takako Hiratsuka, Yoshitada Miyoshi, Yasutake Tomata, Shu Zhang, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Cognitive impairment and depressive symptoms lead to biases in self-evaluated masticatory performance among community-dwelling older Japanese adults: the Tsurugaya Project. Journal of Dentistry, 2020 Jun 6:103403. doi: 10.1016/j.jdent.2020.103403.

(2019年)

  1. Takamasa Komiyama, Takashi Ohi, Yasutake Tomata, Fumiya Tanji, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Dental status is associated with incident functional disability in community-dwelling older Japanese: a prospective cohort study using propensity score matching. Journal of Epidemiology, 2019 Jan 25.
  2. Nao Furukawa, Yoshihiko Ito, Yasue Tanaka*, Wakana Ito, Yoshinori Hattori. Preliminary exploration for evaluating acuity of oral texture perception. Journal of Texture Studies, 2019 Mar 13; 1-7.
  3. Gaku Ohwada, Shunsuke Minakuchi, Yusuke Sato, Hisatomo Kondo, Taro Nomura, Akito Tsuboi, Guang Hong, Yoshihiko Itoh, Yasuhiko Kawai, Suguru Kimoto, Atsuko Gunji, Asako Suzuki, Tetsuya Suzuki, Katsuhiko Kimoto, Noriyuki Hoshi, Makiko Saita, Yoshikazu Yoneyama, Yohei Sato, Masakazu Morokuma, Joji Okazaki, Takeshi Maeda, Kenichiro Nakai, Tetsuo Ichikawa, Kan Nagao, Keiko Fujimoto, Hiroshi Murata, Tadafumi Kurogi, Kazuhiro Yoshida, Masahiro Nishimura, Yasuhiro Nishi, Mamoru Murakami, Toshio Hosoi, Taizo Hamada. Subjective evaluation of denture adhesives: A multicenter randomized controlled trial. JDR Clinical & Translational Research, 2019 Apr 11:2380084419837607. doi: 10.1177/2380084419837607.
  4. Takashi Ohi, Takamasa Komiyama, Yoshitada Miyoshi, Takahisa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. The association between bilateral maximum occlusal force and all-cause mortality among community-dwelling older adults: The Tsurugaya project. Journal of Prosthodontic Research, 10.1016/j.jpor.2019.08.005.
  5. Takako Hiratsuka, Takamasa Komiyama*, Takashi Ohi, Fumiya Tanji, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Contribution of systemic inflammation and nutritional status to the relationship between tooth loss and mortality in a community-dwelling older Japanese population: a mediation analysis of data from the Tsurugaya Project. Clinical Oral Investigations, 10.1007/s00784-019-03072-y. Accepted 30 August 2019, First Online 04 September 2019
  6. Yasuhiro Nishi, Taro Nomura, Mamoru Murakami, Yasuhiko Kawai, Masahiro Nishimura, Hisatomo Kondo, Yoshihiko Ito, Akito Tsuboi, Guang Hong, Suguru Kimoto, Atsuko Gunji, Asako Suzuki, Gaku Ohwada, Shunsuke Minakuchi, Yusuke Sato, Tetsuya Suzuki, Katsuhiko Kimoto, Noriyuki Hoshi, Makiko Saita, Yoshikazu Yoneyama, Yohei Sato, Masakazu Morokuma, Joji Okazaki, Takeshi Maeda, Kenichiro Nakai, Tetsuo Ichikawa, Kan Nagao, Keiko Fujimoto, Hiroshi Murata, Tadafumi Kurogi, Kazuhiro Yoshida, Toshio Hosoi, Taizo Hamada. Effect of denture adhesives on oral moisture: A multicenter randomized controlled trial. Journal of Prosthodontis Research 2019 Sep 6. pii: S1883-1958(19)30311-1. 10.1016/j.jpor.2019.08.004.
  7. Tsuyoshi Fujii, Satoshi Yamaguchi*, Yul-wan Sung, Makoto Watanabe, Yoshinori Hattori. Correlation between changes in the transverse relaxation time and electromyographic measurements of the superficial masseter and temporal muscles. Magnetic Resonance in Medical Sciences, Article ID: tn.2019-0035, 10.2463/mrms.tn.2019-0035.
  8. 伊藤佳彦, 古川奈緒, 伊藤和佳奈, 田中恭恵*, 服部佳功. とろみ調整食品の添加が口腔のざらつき感覚に及ぼす影響. 日本全身咬合学会雑誌 2019; 25(2): 44―48.

(2018年)

  1. Satoshi Yamaguchi, Chika Okada, Yoshihiko Watanabe, Makoto Watanabe, Yoshinori Hattori. Analysis of masticatory muscle coordination during unilateral single-tooth clenching using muscle functional magnetic resonance imaging. Journal of Oral Rehabilitation, 2018 Jan; 45(1): 9―16.
  2. Feng Luo, Guang Hong, Hiroyuki Matsui, Kosei Endo, Qianbing Wan, Keiichi Sasaki. Initial osteoblast adhesion and subsequent differentiation on zirconia surfaces are regulated by integrins and heparin-sensitive molecule. Int J Nanomedicine, 2018 Nov 19; 13: 7657-7667.
  3. Takashi Ohi, Takamasa Komiyama, Yoshitada Miyoshi, Takahasa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Maximum Occlusal Force and Incident Functional Disability in Older Adults: The Tsurugaya Project. JDR Clinical & Translational Research, 2018 Apr; 3(2): 195―202.
  4. Shigeto Koyama, Takeshi Fuji, Takashi Ohi, Kenji Kadowaki, Nobuhiro Yoda, Keiichi Sasaki. Practice-Based Longitudinal Study of Multifactorial Risk Assessment for Periodontal Condition and Survival of Remaining Teeth in Patients with Removable Partial Dentures. International Journal of Prosthodontics, 2018 September/October; 31(5): 502-8.
  5. Sho Saito, Takashi Ohi, Takahisa Murakami, Takamasa Komiyama, Yoshitada Miyoshi, Kosei Endo, Michihiro Satoh, Kei Asayama, Ryusuke Inoue, Masahiro Kikuya, Hirohito Metoki, Yutaka Imai, Takayoshi Ohkubo, Yoshinori Hattori. Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the Ohasama study. BMC Oral Health, 2018 Aug 20; 18(1): 142.
  6. Takamasa Komiyama, Takashi Ohi, Yoshitada Miyoshi, Takahisa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Relationship between status of dentition and incident functional disability in an elderly Japanese population: prospective cohort study of the Tsurugaya Project. Journal of Prosthodontic Research, 2018 Oct; 62(4): 443―448.

(2017年)

  1. J Liu, G Hong, YH Wu, Kosei Endo, JM Han, H Kumamoto, T Wada, H Kato, P Gao, Keiichi Sasaki. A novel method of surface modification by electrochemical deoxidation: Effect on surface characteristics and initial bioactivity of zirconia. J Biomed Mater Res B Appl Biomater. 2017 Nov; 105(8): 2641―2652.
  2. 伊藤佳彦, 遠藤耕生, 田中恭恵, 山口哲史, 服部佳功. 舌―硬口蓋間のテクスチャー感覚と舌乳頭の形態的特徴との関係: 予備的研究. 日本顎口腔機能学会雑誌 2017; 23(2): １―11.
  3. 猪狩洋平, 服部佳功. 加齢に伴う最大咬合力の変化: メタ解析による検討. 東北大学歯学雑誌 2017; 34(2)/35(1): 10―14.
  4. 田中恭恵, 古川奈緒, 服部佳功. 嚥下障害者用増粘剤（とろみ調整食品）が咀嚼能率に及ぼす影響 ～ピーナッツ咀嚼における検討～. 東北大学歯学雑誌 2017; 34(2)/35(1): 15―19.
  5. 山口哲史, 岡田知佳, 渡部芳彦, 渡辺誠, 服部佳功. mfMRIによる咀嚼筋局所活動分布における多様性の可視化と共通傾向の解析. 東北大学歯学雑誌 2017; 34(2)/35(1): 20―26.

(2016年)

  1. Chika Okada, Satoshi Yamaguchi, Yoshihiko Watanabe, Makoto Watanabe, Yoshinori Hattori. Evaluation of masticatory activity during unilateral single tooth clenching using muscle functional magnetic resonance imaging. Journal of Oral Rehabilitation, 2016 Aug; 43(8): 583―590.
  2. Minoru Takahashi, Satoshi Yamaguchi, Tsuyoshi Fujii, Makoto Watanabe, Yoshinori Hattori. Contribution of each masticatory muscle to the bite force determined by magnetic resonance imaging using a novel metal-free bite force gauge and an index of total muscle activity. Journal of Magnetic Resonance Imaging, 2016 Oct; 44(4): 804―813.
  3. Takamasa Komiyama, Takashi Ohi, Yoshitada Miyoshi, Takahisa Murakami, Akito Tsuboi, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori. Association between tooth loss, receipt of dental care, and functional disability in an elderly Japanese population: The Tsurugaya Project. Journal of the American Geriatrics Society, 2016 Dec; 64(12): 2495-2502.
  4. 服部佳功, 枝広あや子, 渡邊裕, 平野浩彦, 古屋純一, 中島純子, 田村文誉, 北川昇, 堀一浩, 原哲也, 吉川峰加, 西恭宏, 永尾寛, 市川哲雄, 櫻井薫（一般社団法人日本老年歯科医学会ガイドライン委員会）. 認知症患者の歯科治療に対する疑問と問題点: Clinical Question調査から. 老年歯科医学 2016; 31(1): 3―8.

分野問い合わせ

E-mail：yoshinori.hattori.b4＊tohoku.ac.jp（＊を＠に変えてください。）
TEL：022-717-8396
FAX：022-717-8396

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