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各講座・研究分野一覧へ戻る

共創歯学分野

分野の紹介

当分野では、融合知教育による口腔科学を広く学際的に俯瞰できる人材養成を視野に入れ、異分野融合研究、産官学民連携研究を基軸としたトランスレーショナルリサーチおよびレギュラトリーサイエンスに関する研究に取り組んでいます。

具体的には、異分野融合研究により、ニッケルフリー形状記憶合金、生体吸収性金属ガラス、可視光応答性酸化チタンなど最先端医療用材料を開発し、様々な革新的な医療機器・材料へ応用しています。加えて、独立行政法人医薬品医療機器総合機構（PMDA）など規制当局との連携により、各種医療機器・材料に関する国際・国内ガイドラインの策定などレギュラトリーサイエンスに関する研究にも取り組んでいます。

当分野は、医工学研究科において協力講座として「先進歯科医工学分野」を運営しており、歯学部出身者だけでなく、工学、医学、薬学、文学など多様な背景を持つスタッフや学生が在籍し、異分野融合研究、産官学民連携研究を推進しています。

教員構成

主な研究テーマ

  • 医療機器・材料開発に関するトランスレーショナルリサーチ
  • 産官学民連携によるレギュラトリーサイエンス
  • 各種医療機器・材料に関する国際・国内ガイドラインの策定
  • 異分野融合研究による先端医療機器・材料の開発
  • 最新AI技術を応用した医療システムの開発
  • 産学官連携による新しい機能性食品開発
  • 口腔機能の脳機能学的解析
  • 次世代放射光の歯科領域への応用

最近の業績

  1. Chigama H, Kanetaka H, Furuya M, Yokota K, Kawashita M: Indirect cytotoxicity evaluations of antibacterial raw silk fabric doped with calcium, copper, and zinc on fibroblasts and osteoblasts. J Biomater Appl: 2022. (in press)
  2. Li K, Liang L, Du P, Cai Z, Xiang T, Kanetaka H, Wu H, Xie G: Mechanical properties and corrosion resistance of powder metallurgical Mg-Zn-Ca/Fe bulk metal glass composites for biomedical application. J Mater Sci Technol 103: 73-83, 2022.
  3. Toriyabe A, Chiua W T, Umise A, Tahara M, Goto K, Kanetaka H, Hanawa T, Hosoda H: Mechanical property enhancement of the Ag–tailored Au–Cu–Al shape memory alloy via the ductile phase toughening. Intermetallics 139: 107349, 2021.
  4. Yamaguchi M, Ma T, Tadaki D, Hirano-Iwata A, Watanabe Y, Kanetaka H, Fujimori H, Takemoto E, Niwano M: Bactericidal activity of bulk nanobubbles through active oxygen species generation. Langmuir 37(32): 9883–9891, 2021.
  5. Wang Y, Yoshida Y, Kamiie J, Shiwaku Y, Suzuki O, Furuya M, Yokota K, Kanetaka H, Yokoi T, Kawashita M: Proteomic identification of serum proteins to induce osteoconductivity of hydroxyapatite. Dent Mater J 40(6): 1428–1436, 2021.
  6. Shibata M, Kanetaka H, Furuya M, Yokota K, Ogawa T, Kawashita M: Cytotoxicity evaluation of iron nitride nanoparticles for biomedical applications. J Biomed Mater Res 109(10): 1784-1791, 2021.
  7. Kubota M, Yokoi T, Ogawa T, Saito S, Furuya M, Yokota K, Kanetaka H, Jeyadevan B, Kawashita M: In-vitro heat-generating and apatite-forming abilities of PMMA bone cement containing TiO2 and Fe3O4. Ceram Int 47(9): 12292–12299, 2021.
  8. Kamitakahara M, Ishii A, Matsubara H, Kawashita M, Furuya M, Kanetaka H: Fabrication and evaluation of ascorbic acid phosphate-loaded spherical porous hydroxyapatite/octacalcium phosphate granules. Journal of the Ceramic Society of Japan 129(1): 60-65, 2021.
  9. Yamaguchi M, Abe H, Teng M, Tadaki D, Hirano-Iwata A, Kanetaka H, Watanabe Y, Niwano M: Bactericidal activity of TiO2 nanotube thin films on Si by photocatalytic generation of active oxygen species. Langmuir 36(42): 12668-12677, 2020.
  10. Kubota M, Yokoi T, Ogawa T, Saito S, Furuya M, Yokota K, Kanetaka H, Jeyadevan B, Kawashita M: Setting behavior, mechanical properties, and heat generation under AC magnetic fields of Fe3O4/TiO2/PMMA composite bone cement. Medical devices & sensors 3(6): e10114, 2020.
  11. Kato T, Sekiguchi Y, Honda K, Izumi S, Kanetaka, H: Comparison of handrail reaction force between two different handrails during sit-to-stand movement in the elderly. Clin Biomech 80: 105130, 2020.
  12. Sekiguchi Y, Honda K, Phakdepiboon T, Jinde M, Kato T, Kanetaka H, Izumi S: Effects of shelf bar assistance on kinetic control during sit-to-stand in healthy young and elderly subjects Journal of Biomechanics. J Biomech 106: 109822, 2020.
  13. Sasaki S, Zheng Y, Mokudai T, Kanetaka H, Tachikawa M, Kanzaki M, Kaneko T: Continuous release of O2−/ONOO− in plasma-exposed HEPES-buffered saline promotes TRP channel-mediated uptake of a large cation. Plasma Processes and Polymers 17(10): e1900257, 2020.
  14. Chigama H, Yokoi T, Furuya M, Yokota K, Kanetaka H, Kawashita M: Apatite formation and bacterial growth on raw silk fabric heated in argon gas. J Mater Sci Mater Med 31(49): 31-49, 2020.
  15. Kamezawa C, Numano T, Kawabata Y, Kanetaka H, Furuya M, Yokota K, Kato H, Yoneyama A, Hyodo,K, Yashiro W: X-ray elastography by visualizing propagating shear waves. Jpn. Appl. Phys. Express 13(4): 042004, 2020.
  16. Kawashita M, Ueno S, Handa S, Furuya M, Yokota K, Kanetaka H.: In vitro evaluation of doxorubicin-eluting porous titania microspheres for transcatheter arterial chemoembolization. J. Asian Ceram. Soc. 8:10-20, 2020.
  17. Iwatsu M, Kanetaka H, Mokudai T, Ogawa T, Kawashita M, Sasaki K: Visible light-induced photocatalytic and antibacterial activity of N-doped TiO2.J Biomed Mater Res B Appl Biomater 108(2): 451-459, 2020.
  18. Hihara H, Kanetaka H, Kanno A, Shimada E, Koeda S, Kawashima R, Nakasato N, Sasaki K: Somatosensory evoked magnetic fields of periodontal mechanoreceptors. Heliyon 6(1): e03244, 2020.
  19. Chigama H, Kanetaka H, Furuya M, Yokota K, Kawashita M: Evaluation of apatite-forming ability and antibacterial activity of raw silk fabrics doped with metal ions. Mater Trans 60(5): 808-814, 2019.
  20. Xie G, Kanetaka H, Kato H, Qin F, Wang W: Porous Ti-based bulk metallic glass with excellent mechanical properties and good biocompatibility. Intermetallics 105: 153-162, 2019.
  21. Kawashita M, Iwabuchi Y, Suzuki K, Furuya M, Yokota K, Kanetaka H: Surface structure and in vitro apatite-forming ability of titanium doped with various metals. Colloids Surf A Physicochem Eng Asp 555: 558-564, 2018.
  22. Kanetaka H, Mokudai T, Xie G: Large-size biodegradable Ca-Mg-Zn bulk metallic glass for medical use developed by spark plasma sintering. Tohoku Univ. Dent. J. 36/37: 17-23, 2018.
  23. Koyama S, Kanetaka H, Sagehashi Y, Sasaki K, Sato N: Availability of cosmetic treatment using novel cosmetics-based material on patients with craniofacial concavity. J Prosthodont Res 62(3), 379-382, 2018.
  24. Hashimoto M, Ogawa T, Kitaoka S, Muto S, Furuya M, Kanetaka H, Abe M, Yamashita H: Control of surface potential and hydroxyapatite formation on TiO2 scales containing nitrogen-related defects. Acta Mater 155: 379-385, 2018.
  25. Kanetaka H, Liu G, Li Z, Miyazaki T, Furuya M, Kudo T, Kawashita M: TiO2 microspheres containing magnetic nanoparticles for intra-arterial hyperthermia. J Biomed Mater Res B Appl Biomater 105B (8): 2308-2314, 2017.
  26. Tominami K, Kanetaka H, Sasaki S, Mokudai T, Kaneko T, Niwano Y: Cold atmospheric plasma enhances osteoblast differentiation. PLoS ONE 12(7): e0180507, 2017.
  27. Hihara H, Kanetaka H, Kanno A, Koeda S, Nakasato N, Kawashima R, Sasaki K: Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields. PLoS ONE 12(6): e0179323, 2017.
  28. Osaki Y, Hashi S, Yabukami S, Kanetaka H, Ishiyama K: Wireless magnetic position-detection system with four excitation coils. IEEE Sens J 17(14): 4412-4419, 2017.
  29. Sekiguchi Y, Kato T, Honda K, Kanetaka H, Izumi SI: Effects of grab bar on utilized friction and dynamic stability when elderly people enter the bathtub. Clin Biomech 47: 7-13, 2017.
  30. Tominami K, Kanetaka H, Kudo T, Sasaki S, Kaneko T: Apoptotic effects on cultured cells of atmospheric-pressure plasma produced using various gases. Jpn J Appl Phys 55(1S): 01AF03, 2016.
  31. Hashimoto M, Kitaoka S, Kanetaka H: Effect of surface charge of TiO2 particles on hydroxyapatite formation in simulated body fluid. Biomed Mater 27(6): 2409-2415, 2016.
  32. Xiea G, Takada H, Kanetaka H: Development of high performance MgFe alloy as potential biodegradable materials. Mater Sci Eng A Struct Mater 671: 48-53, 2016.
  33. Yamauchi Y, Nogami S, Tanaka K, Shimizu Y, Kanetaka H, Takahashi T: The effect of decortication for periosteal expansion osteogenesis using shape memory alloy mesh device. Clin Implant Dent Relat Res 17(S2): e376-384, 2015.
  34. Liu G, Kawashita M, Li Z, Miyazaki T, Kanetaka H: Sol–gel synthesis of magnetic TiO2 microspheres and characterization of their in vitro heating ability for hyperthermia treatment of cancer. J Sol-Gel Sci Technol 75(1): 90-97, 2015.
  35. Yabukami S, Takahashi K, Ozawa T, Fujioka O, Nagano T, Hashi S, Kanetaka H: Tracking system for magnetic wireless marker using field programmable gate array. J Magn Soc Jpn 39: 156-160, 2015.
  36. Nunome S, Kanetaka H, Kudo T, Endoh K, Hosoda H, Igarashi K: In vitro evaluation of biocompatibility of Ti-Mo-Sn-Zr superelastic alloy. J Biomater Appl 30(1): 119-130, 2015.

分野問い合わせ

E-mail：hiroyasu.kanetaka.e6*tohoku.ac.jp （*を＠に変えてください。）
TEL：022-717-8415
FAX：022-717-8415

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