Liaison Center for Innovative DentistryDivision of Interdisciplinary Co-Creation (ICC-Division)

In order to systematize the field of oral science by joining together the different areas of expertise, this section promotes advanced dental research, interdisciplinary integration research, and industry / government / academic collaboration, based on the concept of Interface Oral Health Science, and coordinates research activities for the dentistry of a next generation.


Topics of Research

  • Translational research on medical device / material development
  • Regulatory science through industry-government-academia collaboration
  • Formulation of international and domestic guidelines for various medical devices and materials
  • Development of advanced medical device / material through interdisciplinary research
  • Development of medical system applying the latest AI technology
  • Development of new functional food through industry-academia-government collaboration
  • Brain function analysis for oral functions
  • Application of next-generation synchrotron radiation to the dental field

Recent Publications

  1. Chigama H, Kanetaka H, Furuya M, Yokota K, Kawashita M: Indirect cytotoxicity evaluations of antibacterial raw silk fabric doped with calcium, copper, and zinc on fibroblasts and osteoblasts. J Biomater Appl: 2022. (in press)
  2. Li K, Liang L, Du P, Cai Z, Xiang T, Kanetaka H, Wu H, Xie G: Mechanical properties and corrosion resistance of powder metallurgical Mg-Zn-Ca/Fe bulk metal glass composites for biomedical application. J Mater Sci Technol 103: 73-83, 2022.
  3. Toriyabe A, Chiua W T, Umise A, Tahara M, Goto K, Kanetaka H, Hanawa T, Hosoda H: Mechanical property enhancement of the Ag–tailored Au–Cu–Al shape memory alloy via the ductile phase toughening. Intermetallics 139: 107349, 2021.
  4. Yamaguchi M, Ma T, Tadaki D, Hirano-Iwata A, Watanabe Y, Kanetaka H, Fujimori H, Takemoto E, Niwano M: Bactericidal activity of bulk nanobubbles through active oxygen species generation. Langmuir 37(32): 9883–9891, 2021.
  5. Wang Y, Yoshida Y, Kamiie J, Shiwaku Y, Suzuki O, Furuya M, Yokota K, Kanetaka H, Yokoi T, Kawashita M: Proteomic identification of serum proteins to induce osteoconductivity of hydroxyapatite. Dent Mater J 40(6): 1428–1436, 2021.
  6. Shibata M, Kanetaka H, Furuya M, Yokota K, Ogawa T, Kawashita M: Cytotoxicity evaluation of iron nitride nanoparticles for biomedical applications. J Biomed Mater Res 109(10): 1784-1791, 2021.
  7. Kubota M, Yokoi T, Ogawa T, Saito S, Furuya M, Yokota K, Kanetaka H, Jeyadevan B, Kawashita M: In-vitro heat-generating and apatite-forming abilities of PMMA bone cement containing TiO2 and Fe3O4. Ceram Int 47(9): 12292–12299, 2021.
  8. Kamitakahara M, Ishii A, Matsubara H, Kawashita M, Furuya M, Kanetaka H: Fabrication and evaluation of ascorbic acid phosphate-loaded spherical porous hydroxyapatite/octacalcium phosphate granules. Journal of the Ceramic Society of Japan 129(1): 60-65, 2021.
  9. Yamaguchi M, Abe H, Teng M, Tadaki D, Hirano-Iwata A, Kanetaka H, Watanabe Y, Niwano M: Bactericidal activity of TiO2 nanotube thin films on Si by photocatalytic generation of active oxygen species. Langmuir 36(42): 12668-12677, 2020.
  10. Kubota M, Yokoi T, Ogawa T, Saito S, Furuya M, Yokota K, Kanetaka H, Jeyadevan B, Kawashita M: Setting behavior, mechanical properties, and heat generation under AC magnetic fields of Fe3O4/TiO2/PMMA composite bone cement. Medical devices & sensors 3(6): e10114, 2020.
  11. Kato T, Sekiguchi Y, Honda K, Izumi S, Kanetaka, H: Comparison of handrail reaction force between two different handrails during sit-to-stand movement in the elderly. Clin Biomech 80: 105130, 2020.
  12. Sekiguchi Y, Honda K, Phakdepiboon T, Jinde M, Kato T, Kanetaka H, Izumi S: Effects of shelf bar assistance on kinetic control during sit-to-stand in healthy young and elderly subjects Journal of Biomechanics. J Biomech 106: 109822, 2020.
  13. Sasaki S, Zheng Y, Mokudai T, Kanetaka H, Tachikawa M, Kanzaki M, Kaneko T: Continuous release of O2−/ONOO− in plasma-exposed HEPES-buffered saline promotes TRP channel-mediated uptake of a large cation. Plasma Processes and Polymers 17(10): e1900257, 2020.
  14. Chigama H, Yokoi T, Furuya M, Yokota K, Kanetaka H, Kawashita M: Apatite formation and bacterial growth on raw silk fabric heated in argon gas. J Mater Sci Mater Med 31(49): 31-49, 2020.
  15. Kamezawa C, Numano T, Kawabata Y, Kanetaka H, Furuya M, Yokota K, Kato H, Yoneyama A, Hyodo,K, Yashiro W: X-ray elastography by visualizing propagating shear waves. Jpn. Appl. Phys. Express 13(4): 042004, 2020.
  16. Kawashita M, Ueno S, Handa S, Furuya M, Yokota K, Kanetaka H.: In vitro evaluation of doxorubicin-eluting porous titania microspheres for transcatheter arterial chemoembolization. J. Asian Ceram. Soc. 8:10-20, 2020.
  17. Iwatsu M, Kanetaka H, Mokudai T, Ogawa T, Kawashita M, Sasaki K: Visible light-induced photocatalytic and antibacterial activity of N-doped TiO2.J Biomed Mater Res B Appl Biomater 108(2): 451-459, 2020.
  18. Hihara H, Kanetaka H, Kanno A, Shimada E, Koeda S, Kawashima R, Nakasato N, Sasaki K: Somatosensory evoked magnetic fields of periodontal mechanoreceptors. Heliyon 6(1): e03244, 2020.
  19. Chigama H, Kanetaka H, Furuya M, Yokota K, Kawashita M: Evaluation of apatite-forming ability and antibacterial activity of raw silk fabrics doped with metal ions. Mater Trans 60(5): 808-814, 2019.
  20. Xie G, Kanetaka H, Kato H, Qin F, Wang W: Porous Ti-based bulk metallic glass with excellent mechanical properties and good biocompatibility. Intermetallics 105: 153-162, 2019.
  21. Kawashita M, Iwabuchi Y, Suzuki K, Furuya M, Yokota K, Kanetaka H: Surface structure and in vitro apatite-forming ability of titanium doped with various metals. Colloids Surf A Physicochem Eng Asp 555: 558-564, 2018.
  22. Kanetaka H, Mokudai T, Xie G: Large-size biodegradable Ca-Mg-Zn bulk metallic glass for medical use developed by spark plasma sintering. Tohoku Univ. Dent. J. 36/37: 17-23, 2018.
  23. Koyama S, Kanetaka H, Sagehashi Y, Sasaki K, Sato N: Availability of cosmetic treatment using novel cosmetics-based material on patients with craniofacial concavity. J Prosthodont Res 62(3), 379-382, 2018.
  24. Hashimoto M, Ogawa T, Kitaoka S, Muto S, Furuya M, Kanetaka H, Abe M, Yamashita H: Control of surface potential and hydroxyapatite formation on TiO2 scales containing nitrogen-related defects. Acta Mater 155: 379-385, 2018.
  25. Kanetaka H, Liu G, Li Z, Miyazaki T, Furuya M, Kudo T, Kawashita M: TiO2 microspheres containing magnetic nanoparticles for intra-arterial hyperthermia. J Biomed Mater Res B Appl Biomater 105B (8): 2308-2314, 2017.
  26. Tominami K, Kanetaka H, Sasaki S, Mokudai T, Kaneko T, Niwano Y: Cold atmospheric plasma enhances osteoblast differentiation. PLoS ONE 12(7): e0180507, 2017.
  27. Hihara H, Kanetaka H, Kanno A, Koeda S, Nakasato N, Kawashima R, Sasaki K: Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields. PLoS ONE 12(6): e0179323, 2017.
  28. Osaki Y, Hashi S, Yabukami S, Kanetaka H, Ishiyama K: Wireless magnetic position-detection system with four excitation coils. IEEE Sens J 17(14): 4412-4419, 2017.
  29. Sekiguchi Y, Kato T, Honda K, Kanetaka H, Izumi SI: Effects of grab bar on utilized friction and dynamic stability when elderly people enter the bathtub. Clin Biomech 47: 7-13, 2017.
  30. Tominami K, Kanetaka H, Kudo T, Sasaki S, Kaneko T: Apoptotic effects on cultured cells of atmospheric-pressure plasma produced using various gases. Jpn J Appl Phys 55(1S): 01AF03, 2016.
  31. Hashimoto M, Kitaoka S, Kanetaka H: Effect of surface charge of TiO2 particles on hydroxyapatite formation in simulated body fluid. Biomed Mater 27(6): 2409-2415, 2016.
  32. Xiea G, Takada H, Kanetaka H: Development of high performance MgFe alloy as potential biodegradable materials. Mater Sci Eng A Struct Mater 671: 48-53, 2016.
  33. Yamauchi Y, Nogami S, Tanaka K, Shimizu Y, Kanetaka H, Takahashi T: The effect of decortication for periosteal expansion osteogenesis using shape memory alloy mesh device. Clin Implant Dent Relat Res 17(S2): e376-384, 2015.
  34. Liu G, Kawashita M, Li Z, Miyazaki T, Kanetaka H: Sol–gel synthesis of magnetic TiO2 microspheres and characterization of their in vitro heating ability for hyperthermia treatment of cancer. J Sol-Gel Sci Technol 75(1): 90-97, 2015.
  35. Yabukami S, Takahashi K, Ozawa T, Fujioka O, Nagano T, Hashi S, Kanetaka H: Tracking system for magnetic wireless marker using field programmable gate array. J Magn Soc Jpn 39: 156-160, 2015.
  36. Nunome S, Kanetaka H, Kudo T, Endoh K, Hosoda H, Igarashi K: In vitro evaluation of biocompatibility of Ti-Mo-Sn-Zr superelastic alloy. J Biomater Appl 30(1): 119-130, 2015.

Laboratory Contacts