Research

Disease Management DentistryComprehensive Dentistry

The Division of Comprehensive Dentistry aims to serve high-quality comprehensive dental care and also practice the management of clinical education to dental students and postgraduate residents.

We emphasize a holistic approach to diagnosing oral diseases, considering not only the condition of the oral cavity but also its relationship with systemic health, lifestyle habits, and social environment. Based on these comprehensive diagnoses, we provide high-quality standard treatments and continuous care for common dental diseases, also pursuing integrated support through collaboration with specialized divisions.

To advance the field of General Dentistry, we actively engage in a wide range of research activities that contribute to its further development.

Staff

Topics of Research

  • Development of an Educational Support Program for Clinical Training and Internship Based on AI Technology
  • Medical-Engineering Collaborative Research on an Anomaly Detection Device for Dental Restorations and Prostheses
  • Basic and Clinical Research on Stomatognathic Functions, Orofacial Pain, Sleep Dentistry, Sports Dentistry, and Oral Implantology
  • Development of Oral Medicine-Based Treatments for Taste Disorders and Research on Establishing an Umami Sensitivity Test
  • Research on the Development of a Treatment for Xerostomia Targeting Minor Salivary Glands

Recent Publications

  1. Shigemitsu R, Ogawa T, Sato E, Oliveira AS, Rasmussen J.
    Kinematic classification of mandibular movements in patients with temporomandibular disorders based on PCA.
    Comput Biol Med. 2025. 184:109441.
  2. Sammour SR, Naito H, Kimoto T, Sasaki K, Ogawa T.
    Anomaly detection of retention loss in fixed partial dentures using resonance frequency analysis and machine learning: An in vitro study.
    J Prosthodont Res. 2024. 68(3): 510–519.
  3. Satoh-Kuriwada S, Gotoh S, Shoji N, Uneyama H, Komai M.
    Contribution of kelp dashi liquid to sustainable maintenance of taste sensation and promotion of healthy eating in older adults throughout the umami-taste salivary reflex.
    Front Nutr. 2024 Aug 27;11:1406633.
  4. Saito N, Ogawa T, Shiraishi N, Koide R, Komine H, Yokoyama M, Hanawa S, Sasaki
    K. Difference in the electromyographic behavior of the masticatory and swallowing muscles during cued versus spontaneous swallowing.
    Dysphagia. 2024. 39(3):398-406.
  5. Shimada A, Ogawa T, Sammour S, Narihara T, Kinomura S, Koide R, Noma N, Sasaki K.
    Effectiveness of exercise therapy on pain relief and jaw mobility in patients with pain-related temporomandibular disorders: A systematic review.
    Front Oral Health. 2023. 12:4:1170966.
  6. Ogawa T.
    Prediction of mandibular advancement splint treatment response: moving towards individualized therapy for obstructive sleep apnea.
    Sleep. 2022. 13: 45(6).
  7. Qi J, Miyashita M, Ogawa T, Naito H, Sasaki K.
    Resonance frequency analysis for evaluation of the connecting condition between fixed prostheses and their abutment teeth: An in vitro and finite element analysis study.
    J Prosthet Dent. 2024. 131(5):886-894.
  8. Ogawa T, Sitalaksmi RM, Miyashita M, Maekawa K, et al.
    Effectiveness of the Socket Shield Technique in Dental Implant: A Systematic Review.
    J Prosthodont Res. 2022. 11;66(1): 12-18.
  9. Shobara K, Ogawa T, Shibamoto A, Miyashita M, Ito A, Sitalaksmi RM.
    Osteogenic effect of low-intensity pulsed ultrasound and whole-body vibration on peri-implant bone. An experimental in vivo study.
    Clin Oral Implants Res. 2021. 32(5):641-650.
  10. Shobara K, Ogawa T, Sitalaksmi RM, Ito A, Miyashita M, Shibamoto A, Sasaki K.
    Tightening and Loosening of the Abutment Screw Negatively Affects Implant Osseointegration in the Early Healing Stage in Rat Tibiae.
    Int J Prosthodont. 2021. 34(2):199–203.
  11. Denda Y, Niikura N, Satoh-Kuriwada S, Yokoyama K, Terao M, Morioka T, Tsuda B, Okamura T, Ota Y, Tokuda Y, Sasano T, Shoji N.
    Taste alterations in patients with breast cancer following chemotherapy: a cohort study.
    Breast Cancer. 2020 Sep;27(5):954-962.
  12. Yamazaki Y, Ito T, Ogawa T, Hong G, Yamada Y, Hamada T, Sasaki K.
    Potential of pure cellulose nanofibers as a denture base material.
    J Oral Sci. 2020. 23;63(1): 111-113.
  13. Zou W, Hong G, Yamazaki Y, Takase K, Ogawa T, Washio J, Takahashi N, Sasaki K.
    Use of cellulose nanofibers as a denture immersing solution.
    Dent Mater J. 2020. 31;39(1): 80-88.
  14. Iwatsu M, Kanetaka H, Mokudai T, Ogawa T, Kawashita M, Sasaki K.
    Visible light-induced photocatalytic and antibacterial activity of N-doped TiO2.
    J Biomed Mater Res B Appl Biomater. 2020. 108(2): 451-459.
  15. Matsuda M, Ogawa T, Sitalaksmi RM, Miyashita M, Ito T, Sasaki K.
    Effect of mandibular position achieved using an oral appliance on genioglossus activity in healthy adults during sleep.
    Head Face Med. 2019. 4;15(1):26.
  16. Satoh-Kuriwada S, Shoji N, Miyake H, Watanabe C, Sasano T.
    Effects and Mechanisms of Tastants on the Gustatory-Salivary Reflex in Human Minor Salivary Glands.
    Biomed Res Int. 2018 Jan 31;2018:3847075.
  17. Wang S, Ogawa T, Zheng S, Miyashita M, Tenkumo T, Gu Z, Lian W, Sasaki K.
    The effect of low-magnitude high-frequency loading on peri-implant bone healing and implant osseointegration in beagle dogs.
    J Prosthodont Res. 2018. 62(4): 497-502.
  18. Malik B, Whittle T, Ogawa T, Murray GM.
    Reorganization of motor unit activity at different sites within the masseter muscle during experimental masseter pain.
    Eur J Oral Sci.2018. 126(5): 400-410.
  19. Miyashita M*, Ogawa T*, Naito H, Shibamoto A, Wang AS, Shobara K, Sasaki K.
    Evaluation of implant screw loosening by resonance frequency analysis with triaxial piezoelectric pick-up: in vitro model and in vivo animal study.
    Clin Oral Investig. 2018. 22(5): 2129-2134.
  20. Shibamoto A, Ogawa T, Duyck J, Vandamme K, Naert I, Sasaki K.
    Effect of high-frequency loading and parathyroid hormoneadministration on peri-implant bone healing and osseointegration.
    Int J Oral Sci. 2018. 13; 10(1): 6.
  21. Yamamoto M, Ogawa T, Yokoyama M, Funaki Y, Shobara K, Shibamoto A, Vanegas Sáenz JR, Sasaki K.
    Na18F accumulates on the compressive side of peri-implant bone under immediate loading.
    Odontology. 2018. 106: 232-237.
  22. Suzuki T, Ogawa T, Long J, Vanegas Sáenz JR, Miyashita M, Matsuda M, Sasaki K.
    Periodontal tactile sensation and occlusal loading condition of autotransplanted teeth: A retrospective pilot study.
    J Prosthodont Res. 2018. 62(1): 84-88.
  23. Long J, Ogawa T, Ito T, Matsuda M, Li W, Yu H, Sasaki K.
    Effect of bite openings and mandibular protrusion on genioglossus muscle activity in healthy adults with oral appliance.
    Odontology. 2018. 106(1): 90-95.
  24. Trachootham D, Satoh-Kuriwada S, Lam-Ubol A, Promkam C, Chotechuang N, Sasano T, Shoji N.
    Differences in Taste Perception and Spicy Preference: A Thai-Japanese Cross-cultural Study.
    Chem Senses. 2017; 25;43(1):65-74.
  25. Matsuo Y, Ogawa T, Yamamoto M, Shibamoto A, Sáenz JR, Yokoyama M, Kanda Y, Toyohara J, Sasaki K.
    Evaluation of peri-implant bone metabolism under immediate loading using high-resolution Na18F-PET.
    Clin Oral Investig. 2017. 21(6): 2029-2037.
  26. Ogawa T, Long J, Sutherland K, Chan AS, Sasaki K, Cistulli PA.
    Effect of mandibular advancement splint treatment on tongue shape in obstructive sleep apnea.
    Sleep Breath. 2015. 19(3):857-63.
  27. Satoh-Kuriwada S, Kawai M, Iikubo M, Sekine-Hayakawa Y, Shoji N, Uneyama H, Sasano T.
    Development of an umami taste sensitivity test and its clinical use.
    PLoS One. 2014; 18; 9(4):e95177.
  28. Ogawa T, Vandamme K, Zhang X, Naert I, Possemiers T, Chaudhari A, Sasaki K, Duyck J.
    Stimulation of titanium implant osseointegration through high-frequency vibration loading is enhanced when applied at high acceleration.
    Calcif Tissue Int. 2014; 95(5): 467-75.
  29. Yamamoto M, Ogawa T, Yokoyama M, Koyama S, Sasaki K.
    Influence of immediate and early loading on bone metabolic activity around dental implants in rat tibiae.
    Clin Oral Implants Res. 2014; 25(9): 1084-90.
  30. Ogawa T, Possemiers T, Zhang X, Naert I, Chaudhari A, Sasaki K, Duyck J.
    Influence of whole-body vibration time on peri-implant bone healing: a histomorphometrical animal study.
    J Clin Periodontol. 2011; 38(2): 180-5.
  31. Ogawa T, Zhang X, Naert I, Vermaelen P, Deroose CM, Sasaki K, Duyck J.
    The effect of whole-body vibration on peri-implant bone healing in rats.
    Clin Oral Implants Res. 2011; 22(3): 302-7.
  32. Ogawa T, Suzuki T, Oishi N, Zhang X, Naert I, Sasaki K.
    Tactile sensation and occlusal loading condition of mandibular premolars and molars.
    Odontology. 2011; 99: 193-6.
  33. Ogawa T, Ito T, Cardoso MV, Kawata T, Sasaki K
    Oral appliance treatment for obstructive sleep apnoea patients with severe dental condition.
    J Oral Rehabil. 2011; 38(3): 202-7.
  34. Ogawa T, Dhaliwal S, Naert I, Mine A, Kronstrom M, Sasaki K, Duyck J.
    Effect of tilted and short distal implants on axial forces and bending moments in implants supporting fixed dental prostheses: an in vitro study.
    Int J Prosthodont. 2010; 23(6): 566-73.
  35. Ogawa T, Dhaliwal S, Naert I, Mine A, Kronstrom M, Sasaki K, Duyck J.
    Impact of implant number, distribution and prosthesis material on loading on implants supporting fixed prostheses.
    J Oral Rehabil. 2010; 37: 525-31.

Laboratory Contacts

Research