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Preventive Dentistry


Oral health means not only being free of oral diseases but also being able to perform proper oral functions. Basic oral functions such as eating, speaking and laughing are essential for fully expressing oneself and achieving self-realization. Preventive dentistry aims to help people lead a full-fledged life by keeping their oral conditions healthy and optimal so that they can maintain a wholesome life style throughout life.

The typical image of preventive dentistry has been that of preventing dental caries and periodontal diseases. From the overall perspective of systemic health, however, this only represents a fraction of the means of health promotion. Preventive dentistry integrates with the primary prevention (to be healthy and to prevent initial sickness), the secondary prevention (to prevent illness from getting worse) and the tertiary prevention (to recover and restore the original functions). Thus the philosophy of preventive dentistry is required for everyone who engages in oral health care and treatment.

The division of preventive dentistry investigates oral health and healthcare issues from the standpoint of individuals and communities as a whole.

Faculty configuration

  • Takeyoshi KosekiProf.Takeyoshi Koseki

Topics of Research

  • Oral environment control focusing on saliva, for prophylaxis of dental caries and periodontal disease
  • Developing preventive measures for systemic diseases such as cardiovascular disease and aspiration pneumonia through maintaining oral health
  • Research on halitosis (treatment and application for health education)
  • Health management of oral mucosa under systemic medical intervention (prevention of cancer treatment-induced oral mucositis)
  • Development of community based measures for oral health promotion

Recent Performance

  1. Hosokawa R, Oka K, Yamaza T, Iwata J, Urata M, Xu X, Bringas P Jr, Nonaka K, Chai Y. TGF-beta mediated FGF10 signaling in cranial neural crest cells controls development of myogenic progenitor cells through tissue-tissue interactions during tongue morphogenesis. Dev Biol. 2010 May 1;341(1):186-95.
  2. Hosokawa R, Urata M, Han J, Zehnaly A, Bringas P Jr, Nonaka K, Chai Y. TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development. Dev Biol. 2007 Oct 1;310(1):140-53.
  3. Tanda N, Washio J, Ikawa K, Suzuki K, Koseki T, Iwakura M. A new portable sulfide monitor with a zinc-oxide semiconductor sensor for daily use and field study. J Dent. 2007 Jul;35(7):552-7.
  4. Hosokawa R, Urata MM, Ito Y, Bringas P Jr, Chai Y. Functional significance of Smad2 in regulating basal keratinocyte migration during wound healing. J Invest Dermatol. 2005 Dec;125(6):1302-9.
  5. Nishihara T, Koseki T. Microbial etiology of periodontitis. Periodontol 2000. 2004;36:14-26.

Laboratory Contacts

E-mail:yobou*dent.tohoku.ac.jp (Please change * to @.)